Allergy

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Pet allergy is an allergic reaction to proteins contained in animal dander, saliva, or urine. Some people allergic to pets may develop atopic dermatitis resulting from an immune system response. An allergen is an antigenic substance that stimulates an IgE-mediated type I hypersensitivity reaction in atopic individuals, mostly proteins but also some small molecules that can act as semi-antigens. Cats and dogs are the most important sources of pet allergens and are now the third largest group of inhalant allergens after dust mites and pollen allergens. Seven allergenic protein fractions have been identified in dogs, Can f 1-7, of which Can f 3 is the main allergenic protein fraction in dogs, serum albumin, which can cross-react. GMP proteins produced under strict quality control have the advantages of high purity, high sensitivity, and high stability, and currently play an important role in the field of in vitro diagnosis (IVD) of pet allergy.

Allergy

Allergen Skin Testing

Allergen skin testing is a common allergen provocation test, including intradermal and prick tests. Different allergens are marked on the skin, and then a fine needle punctures the skin surface, allowing the allergen to enter the body and observing whether the patient experiences an allergic reaction. These tests are accurate and reliable and can help patients identify which allergens they are sensitive to and develop further protective measures accordingly.

Serum-Specific IgE Test

The serum-specific IgE test is used to identify allergens by collecting a blood sample from the patient and measuring the level of specific IgE in the body. This test can detect multiple allergens at the same time, including pet hair, dander, and feces. Enzyme-linked immunofluorescence assay (ELISA) is the primary technique for detecting levels of allergen-specific IgE in the blood. Serum-specific IgE testing allows patients to learn which allergens they are allergic to, so prevention and treatment can be targeted.

Creative BioMart focuses on the field of IVD and is committed to providing high-quality GMP-grade native Can f 3 protein and related customized services to meet the different needs of customers.

Reasons to Choose Us

Creative BioMart, as a global leading top-ranking provider of GMP proteins and customized GMP protein services, our products can be used in the study of pet allergy in the IVD field, effectively enhancing diagnostic progress. If you are interested in our services or products, please contact us.

Reference

  1. Vredegoor D W, Willemse T, Chapman M D, et al. (2012). Can f 1 levels in hair and homes of different dog breeds: lack of evidence to describe any dog breed as hypoallergenic[J]. Journal of Allergy and Clinical Immunology. 130(4): 904-909. e7.
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