Large-scale GMP Protein Biomanufacturing Service

Since the entire manufacturing process of GMP proteins meticulously adheres to the GMP (Good Manufacturing Practice) standards, their quality and safety exceed that of regular proteins. With the continuous development of biopharmaceuticals, GMP proteins are now used as powerful tools in drug discovery, in vitro diagnostics, food industry, and other fields. In addition, high-quality GMP proteins can assist in immunological experiments, cell culture, and proteomics research. Large-scale GMP protein production is essential to meet today's ever-increasing demands for drug discovery and production, as well as to provide key raw materials for research.

Creative BioMart is a professional supplier in the field of GMP proteins with a complete and standardized production line, capable of producing GMP-grade high-quality proteins that support biomedicine research.

Figure 1. Schematic diagram of large-scale GMP protein biomanufacturing service process.

Specific Process of Our Service

• Design and Synthesis Gene

Optimize the design and synthesis of target genes according to customer requirements.

• Select Suitable Expression System

According to the requirements of the target protein, select the appropriate one from E. coli, yeast, mammalian cell, and insect cell expression system for the experiment.

• Cloning and Transformation

Insert the target gene into a suitable expression vector and introduce the recombinant plasmid into the host cell to make it express the target protein.

• Cell Line Screening

Screen markers or assays specific to the target gene are employed to confirm the retention of only those cell lines that meet the criteria.

• Large-scale Production

Perform large-scale culture in a suitable medium to increase the yield of the target protein.

• Protein Purification

Remove impurities and other proteins by gel chromatography, ion exchange chromatography, affinity chromatography, and other purification methods to ensure the purity and quality of the protein.

• Detection and Analysis

Quality testing and activity analysis of purified target proteins to ensure that the products comply with GMP standards. To verify the correctness and functionality of GMP proteins, biological activity, and molecular weight need to be measured.

Why Choose Us?

• We offer a comprehensive service platform that covers gene synthesis, vector construction, protein expression, and GMP production.
• Various protein expression systems are available, including GMP-grade yeast protein expression system, GMP-grade E. coli protein expression system, GMP-grade baculovirus-insect cell protein expression system, and GMP-grade mammalian cell protein expression system.
• We observe strict adherence to GMP regulations to ensure the superior quality and purity of our products.
• Large-scale production of GMP proteins can meet increasing demand, while standard laboratories can enhance production efficiency through scale-up processing.

Main Application Areas of GMP Proteins

• Biomedicine. Production of drug candidate compounds, and antibodies for drug discovery in clinical trials.
• In vitro diagnostics. Production of various diagnostic reagents, such as viral antigens, antibodies, etc.
• Bio-industry. GMP proteins serve as primary ingredients in enzyme preparations and food additives.
• Food industry. Production of nutritional supplements, functional foods, etc.
• Cosmetics industry. Manufacture of skin care and hair care products.

Creative BioMart is a prominent manufacturer of GMP proteins that aims to provide customers with a wide range of customizable options and services to fortify their research foundation in the life sciences sector. Should you require further information about our services, please feel free to contact us.