Recombinant Human GCG Protein, GMP Grade


Cat# Product Name Availability Size Price Qty
GCG-087THP Recombinant Human GCG Protein, GMP Grade 10ug $998.00
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Cat#:  GCG-087THP
Common Name:  GCG
Product Name:  Recombinant Human GCG Protein, GMP Grade
Product Overview:  Recombinant Human GCG Protein without tag was expressed in E. coli and was produced in an animal component free process under cGMP guidelines.
Description:  The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Source:  E. coli
Species:  Human
Bio-activity:  5 mg/0.5ml
Molecular Mass:  3752.0 Da
AA Sequence:  HGDGSFSDEMNTILDNLAARDFINWLIQTKITD
Endotoxin:  <0.001 EU/μg by the LAL method
Applications:  Treatment of short bowel syndrome (SBS), malabsorption associated with the removal of the intestine, in adults patients who are dependent on parenteral support.
Usage:  Short bowel syndrome (SBS) and malabsorption
Gene Name:  GCG glucagon [ Homo sapiens (human) ]
Official Symbol:  GCG
Synonyms:  GCG; glucagon; glicentin related polypeptide; GLP1; GLP2; glucagon like peptide 1; glucagon like peptide 2; GRPP; glucagon-like peptide 1; glucagon-like peptide 2; glicentin-related polypeptide;
GeneID:  2641
mRNA Refseq:  NM_002054
Protein Refseq:  NP_002045
MIM:  138030
UniProt ID:  P01275
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Not For Human Consumption!

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