Recombinant Human IGFBP3 Protein, GMP Grade
- Specification
- Related Products
| Cat#: |
IGFBP3-085THP |
| Common Name: |
IGFBP3 |
| Product Name: |
Recombinant Human IGFBP3 Protein, GMP Grade |
| Product Overview: |
Recombinant Human IGFBP3 Protein without tag was produced in an animal component free process under cGMP guidelines. |
| Description: |
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Species: |
Human |
| Molecular Mass: |
Not Available |
| AA Sequence: |
Not Available |
| Endotoxin: |
<0.001 EU/μg of the peptide by the LAL method |
| Purity: |
> 99 % by SDS-PAGE and HPLC analysis |
| Applications: |
Investigated for use/treatment in cancer/tumors (unspecified). |
| Usage: |
Cancer/tumors (unspecified) |
| Gene Name: |
IGFBP3 insulin-like growth factor binding protein 3 [ Homo sapiens (human) ] |
| Official Symbol: |
IGFBP3 |
| Synonyms: |
IGFBP3; insulin-like growth factor binding protein 3; insulin-like growth factor-binding protein 3; acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; BP 53; growth hormone dependent binding protein; IBP3; IGF binding protein 3; IBP-3; IGFBP-3; IGF-binding protein 3; growth hormone-dependent binding protein; BP-53; |
| GeneID: |
3486 |
| mRNA Refseq: |
NM_000598 |
| Protein Refseq: |
NP_000589 |
| MIM: |
146732 |
| UniProt ID: |
P17936 |
Not For Human Consumption!
