Recombinant Human IGFBP3 Protein, GMP Grade
- Specification
- Related Products
| Cat#: |
IGFBP3-085THP |
| Common Name: |
IGFBP3 |
| Product Name: |
Recombinant Human IGFBP3 Protein, GMP Grade |
| Product Overview: |
Recombinant Human IGFBP3 Protein without tag was produced in an animal component free process under cGMP guidelines. |
| Description: |
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
| Species: |
Human |
| Molecular Mass: |
Not Available |
| AA Sequence: |
Not Available |
| Endotoxin: |
<0.001 EU/μg of the peptide by the LAL method |
| Purity: |
> 99 % by SDS-PAGE and HPLC analysis |
| Applications: |
Investigated for use/treatment in cancer/tumors (unspecified). |
| Usage: |
Cancer/tumors (unspecified) |
| Gene Name: |
IGFBP3 insulin-like growth factor binding protein 3 [ Homo sapiens (human) ] |
| Official Symbol: |
IGFBP3 |
| Synonyms: |
IGFBP3; insulin-like growth factor binding protein 3; insulin-like growth factor-binding protein 3; acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; BP 53; growth hormone dependent binding protein; IBP3; IGF binding protein 3; IBP-3; IGFBP-3; IGF-binding protein 3; growth hormone-dependent binding protein; BP-53; |
| GeneID: |
3486 |
| mRNA Refseq: |
NM_000598 |
| Protein Refseq: |
NP_000589 |
| MIM: |
146732 |
| UniProt ID: |
P17936 |
For research use only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
