Recombinant Human IL13 Protein, GMP Grade
- Specification
- Related Products
| Cat#: |
IL13-082THP |
| Common Name: |
IL13 |
| Product Name: |
Recombinant Human IL13 Protein, GMP Grade |
| Product Overview: |
Recombinant Human IL13 Protein without tag was produced in an animal component free process under cGMP guidelines. |
| Description: |
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. |
| Species: |
Human |
| Molecular Mass: |
Not Available |
| AA Sequence: |
Not Available |
| Endotoxin: |
<0.001 EU/μg of the peptide by the LAL method |
| Purity: |
> 99 % by SDS-PAGE and HPLC analysis |
| Applications: |
Investigated for use/treatment in brain cancer. |
| Usage: |
Brain cancer |
| Gene Name: |
IL13 interleukin 13 [ Homo sapiens (human) ] |
| Official Symbol: |
IL13 |
| Synonyms: |
IL13; interleukin 13; interleukin-13; allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness 1 (bronchial asthma); IL 13; MGC116786; MGC116788; MGC116789; P600; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13; |
| GeneID: |
3596 |
| mRNA Refseq: |
NM_002188 |
| Protein Refseq: |
NP_002179 |
| MIM: |
147683 |
| UniProt ID: |
P35225 |
Not For Human Consumption!
