Recombinant Human SERPINA1 Protein, GMP Grade
- Specification
- Related Products
| Cat#: |
SERPINA1-077THP |
| Common Name: |
SERPINA1 |
| Product Name: |
Recombinant Human SERPINA1 Protein, GMP Grade |
| Product Overview: |
Recombinant Human SERPINA1 Protein without tag was expressed in yeast and was produced in an animal component free process under cGMP guidelines. |
| Description: |
The protein encoded by this gene is a serine protease inhibitor belonging to the serpin superfamily whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. This protein is produced in the liver, the bone marrow, by lymphocytic and monocytic cells in lymphoid tissue, and by the Paneth cells of the gut. Defects in this gene are associated with chronic obstructive pulmonary disease, emphysema, and chronic liver disease. Several transcript variants encoding the same protein have been found for this gene. |
| Source: |
Yeast |
| Species: |
Human |
| Molecular Mass: |
Not Available |
| AA Sequence: |
Not Available |
| Endotoxin: |
<0.001 EU/μg of the peptide by the LAL method |
| Purity: |
> 99 % by SDS-PAGE and HPLC analysis |
| Applications: |
Investigated for use/treatment in alpha 1 antitrypsin deficiency, atopic dermatitis, and chronic obstructive pulmonary disease (COPD). |
| Usage: |
Alpha 1 antitrypsin deficiency, atopic dermatitis, and chronic obstructive pulmonary disease (COPD) |
| Gene Name: |
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 [ Homo sapiens (human) ] |
| Official Symbol: |
SERPINA1 |
| Synonyms: |
SERPINA1; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; PI, serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 1; alpha-1-antitrypsin; A1A; A1AT; AAT; alpha 1 antitrypsin; alpha1AT; PI1; protease inhibitor 1 (anti elastase); serpin A1; alpha-1-antiproteinase; alpha-1-antitrypsin null; alpha-1 protease inhibitor; protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin; serine (or cysteine) proteinase inhibitor, clade A, member 1; PI; PRO2275; MGC9222; MGC23330; |
| GeneID: |
5265 |
| mRNA Refseq: |
NM_000295 |
| Protein Refseq: |
NP_000286 |
| MIM: |
107400 |
| UniProt ID: |
P01009 |
Not For Human Consumption!
