Recombinant Human IL6 protein, GMP Grade


Cat# Product Name Availability Size Price Qty
IL6-210THP Recombinant Human IL6 protein, GMP Grade 10ug $998
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Cat#:  IL6-210THP
Common Name:  IL6
Product Name:  Recombinant Human IL6 protein, GMP Grade
Product Overview:  Recombinant Human IL6 protein GMP Grade(NP_000591) was expressed in E. coli.
Source:  E. coli
Species:  Human
Form:  Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol and 0.01% Tween80.
Bio-activity:  Measured by its binding ability in a functional ELISA. Immobilized human IL6 at 10μg/mL (100μL/well) can bind human IL6R-His, the EC50 of human IL6R-His is 0.1-0.5 μg/mL. Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is 0.2-0.8 ng/mL. The specific activity of recombinant human IL-6 is approximately 3.2 x 10^5 IU/μg, which is calibrated against human IL-6 WHO International Standard (NIBSC code: 89/548).
Molecular Mass:  The GMP recombinant human IL6 consists of 184 amino acids and has a calculated molecular mass of 20.9 kDa.
Endotoxin:  Less than 0.01 EU per μg determined by the LAL method.
Purity:  Greater than 95 % as determined by SDS-PAGE.
Storage:  Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution:  It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name:  IL6 interleukin 6 (interferon, beta 2) [ Homo sapiens ]
Official Symbol:  IL6
Synonyms:  IL6; interleukin 6 (interferon, beta 2); IFNB2; interleukin-6; BSF2; HGF; HSF; IL 6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor; IL-6;
GeneID:  3569
mRNA Refseq:  NM_000600
Protein Refseq:  NP_000591
MIM:  147620
UniProt ID:  P05231
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